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PF-00562271 is the benzenesulfonate salt of PF-562271
It has 10- to 200-fold higher IC50 for FGFR1
Intended use:
which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis
allergic rhinitis and atopic dermatitis
Dacomitinib (PF299804, PF299) V-Bottom PF-00562271 is the benzenesulfonate saltDacomitinib (PF299804, PF299) is a potent, irreversible pan ErbB inhibitor, mostly to EGFR with IC50 of 6 nM in a cell free assay, effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation. Phase 2.
US$ 1800.00
US$ 1000.00
US$ 2499.50
