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Human B7-H3 Mouse IgG2a Wildtype Fc Amount:50 µg WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQL

SKU: 49362437853

4.2
USD250.00 USD283.00

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Description

WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQL

Mechetina LV

Osteopetrosis is a rare genetic disease characterized by abnormally dense bone

4-1BBL can promote CD8 T cell expansion as well as protect against autoimmune and transplantation rejection

The higher avidity of CTLA-4 binding is primarily due to it very fast on-rate

Human B7-H3 Mouse IgG2a Wildtype Fc Amount:50 µg WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLB7 H3 is an orphan ligand in the B7 family. Its extended extracellular IgSF domain is unique within the family and is phylogenically found in primates only. B7 H3 is known as a co stimulatory and co inhibitory ligand, even though most studies indicate B7 H3 acts as an inhibitor for T cells functions. Consistent with the inhibitory notion, B7 H3 null mice exhibits an earlier onset of autoimmune disorders. P7105F contains all four extracellular IgV C

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