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2:307-311 (2005)
Biochemical properties of the 75-kDa tumor necrosis factor receptor
Chapoval A
TNF promotes the inflammatory responses that often lead to autoimmune disorders such as rheumatoid arthritis
TNF-alpha receptor
Human TNFR2 Mouse IgG2a Wildtype Fc Amount:10 mg 2:307-311 (2005)TNFR2 is a single pass type I membrane protein and the member of TNFR superfamily containing 4 cysteine rich domains (CRD) repeats. In addition to the full length membrane anchored form, soluble TNFR2 can be generated via two distinct mechanisms: (1) shedding via proteolytic processing of the full membrane anchored from, and (2) translation from an alternatively spliced message encoding the extracellular domains of TNFR2. Interacting protein(s): TNF
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