Human TNFR2 Mouse IgG2a Wildtype Fc Amount:10 mg 2:307-311 (2005)

2:307-311 (2005)

Biochemical properties of the 75-kDa tumor necrosis factor receptor

Chapoval A

TNF promotes the inflammatory responses that often lead to autoimmune disorders such as rheumatoid arthritis

TNF-alpha receptor

Human TNFR2 Mouse IgG2a Wildtype Fc Amount:10 mg 2:307-311 (2005)TNFR2 is a single pass type I membrane protein and the member of TNFR superfamily containing 4 cysteine rich domains (CRD) repeats. In addition to the full length membrane anchored form, soluble TNFR2 can be generated via two distinct mechanisms: (1) shedding via proteolytic processing of the full membrane anchored from, and (2) translation from an alternatively spliced message encoding the extracellular domains of TNFR2. Interacting protein(s): TNF