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complement and other Fc interacting molecules
Most of the biological activity of TNF is mediated by TNFR1
Chapoval A
Ann Hematol
Final candidate Z-MAB®s exhibit excellent CMC and pharmacokinetic properties
Human TNFR1 Mouse IgG2a Aglycosylated Fc protein-tag_His-Flag-Myc complement and other Fc interactingTNFR1, a type I membrane protein, is a prototype of the TNF receptor superfamily. TNF binds with high affinity to two members of the TNFR superfamily, TNFR1 (P55) which is activated by both membrane anchored TNF (tmTNF) and soluble TNF, and TNFR2 (P75) which is activated mainly by tmTNF. Interacting protein(s): TNF (P7113T), TNF (P7113F), TNF (P7113M), LT a (P7006M) Related products: TNF Receptor Superfamily Read all details below including Quick
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