A lot of nonsense turns into machine guns, like Retribution of the Ancients activated for 0, Squee's Toy, Distorting Lens, Helm of Chatzuk, and most hilariously of all, the on-theme Bloodthirsty Blade
Just try plot, foretell, adventure or cascade cards, then apply your Fortune Teller's Talent, Sage of the Beyond, and dip into green for Quilled Greatwurm
Having a card that just lets you sink mana into it to loot is itself a nice thing to have around, and the fact that you can actually eventually get the stuff back that you put on the Bag is nice upside, though it wont come up that often
RECOIL in horror at a doctor's madness in Dismember
Theres also some more unusual themes to help Magic put its own stamp on the setting, especially around Nicol Bolas himself, who turns up in much of the sets flavour text, generally expressing his contempt for all things that arent Nicol Bolas