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To start, we have a couple artifacts that mesh well with flicker / blink effects: Prophetic Prism is all over the place in Pauper, and for good reason

Fortunately you dont have to go to THIS extreme, but I guess this technically counts

Rather, they change the outcome of that event or effect as it happens

Crackle With Power is costly but worth it, dealing massive damage to targets of your choice, perfect for closing out games

And then you look down and its Ghostly Prison, Propaganda, Rhystic Study, Spelltithe Enforcer, Mystic Remora, Aura of Silence, and many other dorks and you have to deal with the difficulty of untapping in the face of Winter Orb, Rising Waters, Tangle Wire, and other effects