P18h (AggFluor Halotag Ligand) Size:100nmol 335 SMILES BrCCCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

335 SMILES BrCCCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism

Product Name Pomalidomide-PEG2-C2-amine HCl Synonyms Pomalidomide-4'-PEG2-C2-amine HCl CAS Number 2245697-87-2 Related CAS 2093416-32-9 (free base) Molecular Formula C19H25ClN4O6 Molecular Weight 440

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Product Name 4-(methoxy-d3)benzonitrile Synonyms 4-(²H3)methoxybenzonitrile CAS Number  1404321-27-2 Related CAS Molecular Formula C8H7NO Molecular Weight 136

P18h (AggFluor Halotag Ligand) Size:100nmol 335 SMILES BrCCCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)P18h is a HaloTag ligand incorporating the fluorogenic AggFluor P18 dye. AggFluor is derived from the synthetic GFP chromophore, 4 hydroxybenzylidene imidazolinone (HBI), and belongs to the class of molecular rotor fluorophores widely used in biological imaging due to their sensitivity to environmental factors such as viscosity. When bound to properly folded proteins, AggFluors are quenched and remain non fluorescent; however, protein misfolding or