Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone Product Name Negative Control of

Product Name Negative Control of Biotin-PEG4-CA Synonyms Biotin-PEG4-PEG2-Heptane CAS Number Related CAS Molecular Formula C32H60N4O9S Molecular Weight 676

Product Name Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C76H93FN12O24 Molecular Weight 1577

the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes

89 SMILES: CCN(CC)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2S([O-])(=O)=O)S(=O)(=O)NCCOCCOCCOCC#C)=[N+](CC)CC)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name Thalidomide-O-PEG1-C2-Br Synonyms Thalidomide-4'-O-PEG1-C2-Br CAS Number n/a Related CAS Molecular Formula C17H17BrN2O6 Molecular Weight 425

Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone Product Name Negative Control ofSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC