Phthalimidinoglutarimide-5'-propargyl-C2-OH amine The water soluble 5-FAM PEG3

The water soluble 5-FAM PEG3 alkyne has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal acetylene group

89 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

405 SMILES [N-]=[N+]=NCCOCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM

Product Name Thalidomide-O-acetamido-C2-alkyne Synonyms Thalidomide-4'-O-acetamido-C2-alkyne CAS Number n/a Related CAS Molecular Formula C19H17N3O6 Molecular Weight 383

Phthalimidinoglutarimide-5'-propargyl-C2-OH amine The water soluble 5-FAM PEG3Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Phthalimidinoglutarimide 5' propargyl C2 OH Synonyms CAS Number 2229714 98 9 Related CAS Molecular Formula C18H18N2O4 Molecular Weight 326. 352 SMILES OCCCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping