Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg Sulforhodamine 101 emits at a

Sulforhodamine 101 emits at a longer wavelength than does either Tetramethylrhodamine or Sulforhodamine B

which recruit the VHL or CRBN-ubiquitin E3 ligases to induce the degradation of SNAP-fusion proteins

535-542 Donovan

S)-AHPC-acetamido-O-PEG6-C1-acid Synonyms CAS Number n/a Related CAS Molecular Formula C38H58N4O13S Molecular Weight 810

652Ex/674Em) is a far-red fluorescent dye that is bright

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg Sulforhodamine 101 emits at aSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing