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DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg NCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

SKU: 89930427767

4.8
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Description

NCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name TMP-POM 7c Synonyms TMP-Pomalidomide 7c CAS Number Related CAS Molecular Formula C36H44N8O10 Molecular Weight 748

The strain in DBCO’s cyclooctyne ring drives the reaction forward by releasing energy when it transitions to the triazole product

and cell-permeable

322 SMILES OC(=O)CCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg NCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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