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Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Size:10mg S)-AHPC-acetamido-O-PEG6-C1-acid Synonyms CAS Number n/a

SKU: 89830262428

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Description

S)-AHPC-acetamido-O-PEG6-C1-acid Synonyms CAS Number n/a Related CAS Molecular Formula C38H58N4O13S Molecular Weight 810

Product Name Thalidomide-propargyl-OH Synonyms Thalidomide-4'-propargyl-OH CAS Number 1216805-67-2 Related CAS Molecular Formula C16H12N2O5 Molecular Weight 312

It can be used in many different diagnostic and therapeutic applications

Rational discovery of molecular glue degraders via scalable chemical profiling

908 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCCN=[N+]=[N-])CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Size:10mg S)-AHPC-acetamido-O-PEG6-C1-acid Synonyms CAS Number n/aSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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