Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE propargyl-gly-m-PEG4 When the probe binds to

When the probe binds to its cellular targets

Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C88H111FN12O22 Molecular Weight 1707

NCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

SNAP-tag can be used alongside other tags like CLIP-tag for multicolor labeling

897 Purity (HPLC) >= 95% Solubility DMSO

Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE propargyl-gly-m-PEG4 When the probe binds toSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate