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DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Pomalidomide Product Name Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS

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Description

Product Name Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C86H145N13O26 Molecular Weight 1777

494Ex/526Em after hydrolysis) is a fluorescein derivative where the fluorescein molecule is modified with two acetyl groups

a DBCO-Lys(m-PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility

2560–2575

DMF Shipping Conditions Room Temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Pomalidomide Product Name Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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