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DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg ZXH-1-161 can be used for

SKU: 84836984913

4.3
USD445.00 USD483.00

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Description

ZXH-1-161 can be used for researching multiple myeloma

419 SMILES OC(=O)CCCCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name 5-FAM PEG3 alkyne Synonyms CAS Number N/A Related CAS Molecular Formula C30H27NO9 Molecular Weight 545

Product Name DOTA-PEG6-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C31H55N5O13 Molecular Weight 705

Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475

DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg ZXH-1-161 can be used forSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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