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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan aniline Product Name CA-amide-PEG3-Biotin Synonyms biotin

SKU: 80015562935

4.6
USD495.00 USD518.00

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Description

Product Name CA-amide-PEG3-Biotin Synonyms biotin Halotag Ligand PEG3 CAS Number N/A Related CAS N/A Molecular Formula C29H53ClN4O8S Molecular Weight 653

Product Name Phthalimidinoglutarimide-5'-C6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C19H24N2O4 Molecular Weight 344

69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

146 SMILES BrC1=CC=C2CN(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It has the spectral properties identical to those of other ROX conjugates

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan aniline Product Name CA-amide-PEG3-Biotin Synonyms biotinSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage

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