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Val-Cit-PAB Size:1g The azide functional group is

SKU: 74053166434

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Description

The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules

Azide has been extensively used in click chemistry

Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C49H60N8O17 Molecular Weight 1033

562 SMILES OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N+]=[N-])C1=CC=C(O)C=C1O2 Purity (HPLC) 98% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

054 SMILES [2H]C([2H])([2H])OC1=CC=CC=C1Br Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Val-Cit-PAB Size:1g The azide functional group isVal Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug. Product Name Val Cit PAB Synonyms VC PAB OH CAS Number 159857 79 1 Related CAS Molecular Formula C18H29N5O4 Molecular Weight 379. 461 Purity (HPLC) >= 95% Solubility DMSO, DMF Shipping

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