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Product Name BG-DBCO Synonyms SNAP-DBCO CAS Number 1820756-74-8 Related CAS Molecular Formula C32H27N7O3 Molecular Weight 557
Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
the acetylene – TMR conjugate is an excellent match to the intense 546 nm spectral line of the mercury-arc laps used in most fuorescence microscopes
Product Name Inavolisib Synonyms GDC-0077 CAS Number 2060571-02-8 Related CAS Molecular Formula C18H19F2N5O4 Molecular Weight 407
Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg no extreme temperatures or solventsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
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