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Product Name Pomalidomide-5'-PEG5-OH Synonyms CAS Number 2641838-56-2 Related CAS Molecular Formula C23H31N3O9 Molecular Weight 493
293 Purity (HPLC) >= 95% Solubility DMSO
a highly potent topoisomerase I inhibitor derived from camptothecin
137 Purity (HPLC) >= 95% Solubility DMSO
SB-715992 CAS Number 336113-53-2 Related CAS Molecular Formula C30H33ClN4O2 Molecular Weight 517
Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan biotin Product Name Pomalidomide-5'-PEG5-OH Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker
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