(S,R,S)-AHPC-CO-PEG3-Br deuterium-labeled-nitrogen Product Name Thalidomide-5'-O-PEG4-C2-acid Synonyms CAS

Product Name Thalidomide-5'-O-PEG4-C2-acid Synonyms CAS Number 2688100-28-7 Related CAS Molecular Formula C24H30N2O11 Molecular Weight 522

459 SMILES [N-]=[N+]=NCCCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

405 SMILES [N-]=[N+]=NCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It is preferred for some complicated biological applications where reproducibility is more critical than material cost since the minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties of the underlying conjugates

94 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

(S,R,S)-AHPC-CO-PEG3-Br deuterium-labeled-nitrogen Product Name Thalidomide-5'-O-PEG4-C2-acid Synonyms CASDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name (S,R,S) AHPC CO PEG3 Br Synonyms CAS Number n a Related CAS Molecular Formula C31H45BrN4O7S Molecular Weight 697. 69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity