Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Size:50mg NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

691 Purity (HPLC) >= 95% Solubility DMSO

26 SMILES CC1(N)CCN(CC1)C1=CN=C(C(N)=N1)C1=C(Cl)C(Cl)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Product Name Thalidomide-C3-PEG1-OH Synonyms Thalidomide-4'-C3-PEG1-OH CAS Number 2416133-06-5 Related CAS Molecular Formula C18H20N2O6 Molecular Weight 360

403 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(NCCOCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Size:50mg NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an