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Fmoc-Val-Ala-PAB(m-PEG4)-PNP linker The payload is Exatecan

SKU: 61873590467

4.1
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Description

The payload is Exatecan

BC-PhN3 is a CLIP-tag substrate containg a phenylazide group for click chemistry applicatoions

Product Name DOTA-C4-alcohol Synonyms CAS Number n/a Related CAS Molecular Formula C20H37N5O8 Molecular Weight 475

The covalent linkage between the HaloTag ligand and HaloTag protein enables rapid isolation and purification

494 Purity (HPLC) >= 95% Solubility DMSO

Fmoc-Val-Ala-PAB(m-PEG4)-PNP linker The payload is ExatecanSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned

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