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Fmoc-Val-Cit-PAB-PNP Size:100mg SPAAC is copper-free

SKU: 50348850561

4.0
USD90.00 USD116.00

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Description

SPAAC is copper-free

293 Purity (HPLC) >= 95% Solubility DMSO

068 Purity (HPLC) >= 95% Solubility DMSO

BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-a-brac (BTB) domain of BCL6 with an IC50 of

NCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB-PNP Size:100mg SPAAC is copper-freeFmoc Val Cit PAB PNP is a cleavable ADC linker used in antibodydrug conjugate (ADC) development, designed to enable enzyme responsive payload release in tumor targeted applications. The ValCit dipeptide is optimized for cathepsin B cleavage in lysosomal environments, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug. The p nitrophenyl (PNP) group functions as an efficient leaving group for conjugation to

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