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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB nitrogen facilitating reliable ADC synthesis for

SKU: 46180646801

4.4
USD195.00 USD215.00

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Description

facilitating reliable ADC synthesis for oncology research

Tunnermann

Product Name Thalidomide-O-acetamido-C4-azide Synonyms Thalidomide-4'-O-acetamido-C4-azide CAS Number 2098488-36-7 Related CAS Molecular Formula C19H20N6O6 Molecular Weight 428

009 Purity (HPLC) >= 95% Solubility DMSO

CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB nitrogen facilitating reliable ADC synthesis forSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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