Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg Product Name Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS

Product Name Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C83H133N11O24 Molecular Weight 1669

A one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging

which reacts with benzylguanine (BG)or chloropyrimidine (CP) derivatives

Product Name DOTA-tris(t-Bu)ester-hexyne Synonyms CAS Number n/a Related CAS Molecular Formula C34H61N5O7 Molecular Weight 651

626 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg Product Name Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,