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It forms a covalent bond with the CLIP-tag protein
Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C52H74N8O21 Molecular Weight 1147
Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
This enables researchers to visualize and track proteins or other cellular structures with minimal background interference
S)-AHPC-CO-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C35H54N4O10S Molecular Weight 722
Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg It forms a covalent bondSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
