DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP halide Product Name DOTA-C5-azide Synonyms CAS

Product Name DOTA-C5-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H38N8O7 Molecular Weight 514

Product Name Thalidomide-5'-O-PEG2-C2-azide Synonyms CAS Number 2640388-57-2 Related CAS Molecular Formula C19H21N5O7 Molecular Weight 431

Product Name CP-Vbn Synonyms SNAP2-Vbn CAS Number Related CAS Molecular Formula C21H19ClN4O2 Molecular Weight 394

64 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

allowing the non-internalized probe to be released from the cell surface using the reducing agent sodium 2-mercaptoethanesulfonate (MESNA)

DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP halide Product Name DOTA-C5-azide Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,