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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg 436 SMILES OCCOCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

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Description

436 SMILES OCCOCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

544 SMILES [N-]=[N+]=NCCOCCOCCOCCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It features a disulfide bond

Product Name: 5(6)-TAMRA azide Synonyms: 5-(and -6)-Carboxytetramethylrhodamine Azide CAS Number: N/A Molecular Formula: C28H28N6O4 Molecular Weight: 512

67 Purity (HPLC) >= 95% Physical Appearance Red Solid Optical Properties Abs/Em Maxima: 558/578 nm Solubility DMSO

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg 436 SMILES OCCOCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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