Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP protac ligand 65 SMILES [2H]C([2H])([2H])N(C1=C(F)C=CC=C1Cl)C([2H])([2H])[2H] Purity (HPLC)

65 SMILES [2H]C([2H])([2H])N(C1=C(F)C=CC=C1Cl)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

85 SMILES: Cl

5(6)-ROX alkyne is an excellent azide-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemitry

Product Name NDB-TM Synonyms CAS Number 871510-38-2 Related CAS Molecular Formula C10H10N4O3S Molecular Weight 266

72 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP protac ligand 65 SMILES [2H]C([2H])([2H])N(C1=C(F)C=CC=C1Cl)C([2H])([2H])[2H] Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP