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MC-Val-Cit-PAB(m-PEG8)-Exatecan cp Product Name 1-(methyl-d3)-2

SKU: 39906041668

4.5
USD495.00 USD545.00

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Description

Product Name 1-(methyl-d3)-2

uorescence of the acetylene – tetramethylrhodamine conjugate as well as of many other rhodamine based probes is pH insensitive between 4 and 9

587 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCN2C(=O)C=CC2=O)=[N+](C)C)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

a transcription factor implicated in Duane Radial Ray syndrome

295 Purity (HPLC) >= 95% Solubility DMSO

MC-Val-Cit-PAB(m-PEG8)-Exatecan cp Product Name 1-(methyl-d3)-2SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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