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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg Product Name DOTA-C2-propanamido-maleimide Synonyms CAS

SKU: 38522724014

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Description

Product Name DOTA-C2-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C25H39N7O10 Molecular Weight 597

Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C107H164N12O29 Molecular Weight 2082

specifically used in the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction

A general strategy to develop cell permeable and fluorogenic probes for multicolour nanoscopy

DBCO has been extensively used in copper-free click chemistry

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg Product Name DOTA-C2-propanamido-maleimide Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage

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