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Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 thus has excellent cell permeability

SKU: 30675879671

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Description

thus has excellent cell permeability

392 Purity (HPLC) >= 95% Solubility DMSO

Zimmermann

S)-AHPC-CO-PEG3-C2-acid Synonyms CAS Number 2140807-42-5 Related CAS Molecular Formula C32H46N4O9S Molecular Weight 662

Product Name Phthalimidinoglutarimide-C3-O-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG2-OH CAS Number n/a Related CAS Molecular Formula C20H26N2O6 Molecular Weight 390

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 thus has excellent cell permeabilitySOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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