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Product Name Thalidomide-C3-PEG1-OH Synonyms Thalidomide-4'-C3-PEG1-OH CAS Number 2416133-06-5 Related CAS Molecular Formula C18H20N2O6 Molecular Weight 360
promoting ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF3 zinc finger domains
the chloro atom in Biotin-PEG4-halo is replaced with a methyl group
1 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCCl)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
031 Purity (HPLC) >= 95% Solubility DMSO
Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-PNP snap Product Name Thalidomide-C3-PEG1-OH Synonyms Thalidomide-4'-C3-PEG1-OHSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating
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