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Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg and Orally Bioavailable Small-Molecule GSPT1/2

SKU: 27329489345

4.4
USD495.00 USD515.00

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Description

and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators

Product Name Phthalimidinoglutarimide-C3-O-C2-amine HCl Synonyms Phthalimidinoglutarimide-4'-C3-O-C2-amine HCl CAS Number 2093387-45-0 Related CAS Molecular Formula C18H24ClN3O4 Molecular Weight 381

BI-3802 has antitumor activity

When the probe binds to its cellular targets

where multiple targets can be visualized simultaneously

Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg and Orally Bioavailable Small-Molecule GSPT1/2SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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