Thalidomide-5'-alkyne-C4-OH Size:50mg Compound AN2 reduces mHTT levels

Compound AN2 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)

promoting ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF3 zinc finger domains

Contains an E3 ligase ligand with a linker and a function group

NCCCCCNS(=O)(=O)C1=CC=C(C(=C1)S([O-])(=O)=O)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

S)-AHPC-acetamido-O-PEG2-C2-Br Synonyms CAS Number n/a Related CAS Molecular Formula C30H43BrN4O7S Molecular Weight 683

Thalidomide-5'-alkyne-C4-OH Size:50mg Compound AN2 reduces mHTT levelsDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Thalidomide 5' alkyne C4 OH Synonyms CAS Number n a Related CAS Molecular Formula C19H18N2O5 Molecular Weight 354. 362 SMILES OCCCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room