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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg DMF Shipping Conditions Room Temperature

SKU: 13426761480

4.1
USD495.00 USD530.00

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Description

DMF Shipping Conditions Room Temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Signal Transduction and Targeted Therapy

The conventional maleimidocaproyl (MC) unit is replaced by Mal-Propionyl-PEG2 moiety to enhance aqueous solubility

Product Name NRX-1933 Synonyms CAS Number 2763260-30-4 Related CAS Molecular Formula C14H9F3N6O2 Molecular Weight 350

Product Name Inavolisib Synonyms GDC-0077 CAS Number 2060571-02-8 Related CAS Molecular Formula C18H19F2N5O4 Molecular Weight 407

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg DMF Shipping Conditions Room TemperatureSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,

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