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Product Name Lenalidomide-CO-C5-amine HCl Synonyms Lenalidomide-4'-CO-C5-amine HCl CAS Number 2284453-73-0 Related CAS Molecular Formula C19H25ClN4O4 Molecular Weight 408
E7820 induce targeted degradation of the splicing factor RBM39 through recruitment of the E3 ubiquitin ligase CRL4DCAF15
68 SMILES Cl
85 SMILES Cl
Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C53H87N7O21 Molecular Weight 1158
Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan featured Product Name Lenalidomide-CO-C5-amine HCl SynonymsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload
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