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HaloTag SiR Ligand
Science 2017
Product Name Lenalidomide-CO-PEG3-Cl Synonyms Lenalidomide-4'-CO-PEG3-Cl CAS Number n/a Related CAS Molecular Formula C22H28ClN3O7 Molecular Weight 481
01 SMILES CNC(=O)COC1=CC2=C(C=CC(=C2)N(C)C2=NC(=NC=C2Cl)N2C[C@@H](C)C[C@@H](C)C2)N(C)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
m-PEG4 is attached to the commonly used self-immolative para-aminobenzyl (PAB) moiety to further increase aqueous solubility
MaP555-Alkyne (cell-permeable fluorogenic dye) rox HaloTag SiR LigandMaP555 Alkyne is is a fluorogenic probe. MaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The
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