These stats certainly place Emrakul amongst the biggest creatures in the game, however, Impervious Greatwurm, Ghalta, Primal Hunger, and other colossally huge creatures have all been implemented into MTG Arena without major difficulty
Since Varragoth only costs three mana to cast, you can start tutoring early for ramp cards like Culling of the Weak, to help you cast your high mana value demons
Karrthus, Tyrant of JundKarrthus, Tyrant of Jund - 12,743 decks, 914 as commander I started typing that this was an oldie-but-goodie compared to the other cards on the list, and then my soul immediately withered at the thought of a card from 2009 being "old." Anyway
And without any dual lands or additional mana fixing, a 16-land deck with an 8/8 split of basics is just barely hitting both minimums
If you have one in mint condition, getting it graded could multiply your cards value dramatically