Infect is a mechanic that does this pretty well, but you can also use spells such as target creature gets -2/-2 until end of turn or something similar
It also blanks lethal attacks, protects combo turns, and lets you survive plays that would normally wipe you out of the game
Disney Lorcana TCG is bringing several thrilling events to this years D23: The Ultimate Disney Fan Event

Advanced Search Sets Random Syntax Ashiok, Wicked Manipulator Azor, the Lawbringer Bond of Agony Cruel Sadist Drain Life Elenda and Azor Fire Covenant Fix What's Broken G'raha Tia, Scion Reborn Gix, Yawgmoth Praetor Gix, Yawgmoth Praetor Hand of Vecna Hatred Hazel of the Rootbloom Hurska Sweet-Tooth Ink-Eyes, Servant of Oni Avatar Karn's Sylex Killing Wave Krumar Initiate Lifestream's Blessing Maralen of the Mornsong Avatar Mask of Griselbrand Meathook Massacre II Mortarion, Daemon Primarch My Genius Knows No Bounds Necro-Impotence Necrologia Nourishing Shoal Ovika, Enigma Goliath Phyrexian Processor Plunge into Darkness Promise of Power Rodolf Duskbringer Roiling Horror Shanna, Purifying Blade Soul Burn Sphinx of the Revelation The Last Ride Tivash, Gloom Summoner Toxic Deluge Tymna the Weaver Tymna the Weaver Vicious Rivalry Vigil for the Lost Volcano Hellion Well of Lost Dreams Winter, Cursed Rider

Vaynes Treachery: Cheap removal for cheap creatures - and if you need to get something bigger out of the way, youll be glad that you have the option to do so